NAISS
SUPR
NAISS Projects
SUPR
One-pot Synthesis of Bio-based Acrylates
Dnr:

NAISS 2026/4-482

Type:

NAISS Small

Principal Investigator:

Alka Karn

Affiliation:

Linköpings universitet

Start Date:

2026-03-17

End Date:

2026-10-01

Primary Classification:

10405: Organic Chemistry

Allocation

Abstract

A sustainable one-pot protocol for the synthesis of biobased acrylates has been developed using readily available starting materials under mild conditions. In this method, maleic anhydride reacts with bio-derived alcohols in the presence of catalytic triphenylphosphine to afford the corresponding acrylate derivatives through nucleophilic activation and subsequent dehydration. The transformation proceeds efficiently in a single step without the need for pre-activation of substrates or harsh reagents, providing a straightforward and atom-economic route to valuable acrylate monomers. The methodology demonstrates good functional group tolerance and moderate to good yields, highlighting its potential as a greener and practical approach for the preparation of renewable acrylate building blocks relevant to polymer and materials chemistry.