NAISS
SUPR
NAISS Projects
SUPR
BAMSE multi omics
Dnr:

sens2026001

Type:

NAISS SENS

Principal Investigator:

Erik Melén

Affiliation:

Karolinska Institutet

Start Date:

2026-02-04

End Date:

2027-03-01

Primary Classification:

30115: Medical Epigenetics and Epigenomics

Webpage:

Allocation

Abstract

We have generated a unique dataset from our BAMSE cohort from RNA and DNA methylation seqencing efforts, as well as proteomics, at SciLifeLab (Uppsala and OLINK Explore - HPA). Now, we will start analyzing the data to determine eQTL, mQTL and pQTL signals of relevance for common, complex diseases such as respiratory and cardiovascular diseases. In addition, environmental exposure effects will be assessed. The BAMSE project has generated numerous high-profile papers in the last years, including NEJM, Science, Lancet, Nature Comm papers, and is supported by the EU (incl ERC), NIH, VR, HLF and others.