Pain chronification
Dnr:
NAISS 2025/6-318
Type:
NAISS Medium Storage
Principal Investigator:
Saida Hadjab
Affiliation:
Karolinska Institutet
Start Date:
2025-10-27
End Date:
2026-11-01
Primary Classification:
10203: Bioinformatics (Computational Biology) (Applications at 10610)
Secondary Classification:
10610: Bioinformatics and Computational Biology (Methods development to be 10203)
Allocation
Abstract
Our aim is i) to provide the first comprehensive and integrative map of the transcriptomic changes in the peripheral sensory system, at the single cell level, in different neuropathic pain models ii) to use this knowledge to investigate whether we can prevent or reverse the epigenetic and transcriptomic state modifications and pain sensitization observed after peripheral nerve injury.