SUPR
Predicting protein interaction surfaces
Dnr:

NAISS 2025/6-153

Type:

NAISS Medium Storage

Principal Investigator:

Gemma Atkinson

Affiliation:

Lunds universitet

Start Date:

2025-05-21

End Date:

2026-06-01

Primary Classification:

30109: Microbiology in the Medical Area

Secondary Classification:

10606: Microbiology (Medical aspects at 30109 and agricultural at 40302)

Allocation

Abstract

In my group, we work on high-throughput discovery of toxin-antitoxin systems and antiphage defense systems in microbial genomes. Our work in this area is high impact, being published in PNAS and MolCell, and we are supported by a generous KAW project grant. We do high throughput searches within bacterial and phage genomes and identify potential novel systems. We use genomic context analyses with our own tools, followed by functional annotation based on sequence and structure analyses.