SUPR
Chromatin landscape in autoreactive B cells
Dnr:

NAISS 2025/22-540

Type:

NAISS Small Compute

Principal Investigator:

Mike Aoun

Affiliation:

Karolinska Institutet

Start Date:

2025-04-07

End Date:

2026-05-01

Primary Classification:

10605: Immunology (Medical aspects at 30110 and agricultural at 40302)

Webpage:

Allocation

Abstract

It is a follow up project to the published findings regarding the existence of autoreactive B cells in the B cell repertoire and its relevance to autoimmune diseases. Now we want to study the transcriptional profile of these cells from the mouse using RNA and ATAC-seq.