Single cell level analysis for cell replacement therapy for Parkinson disease
Dnr:
NAISS 2025/22-366
Type:
NAISS Small Compute
Principal Investigator:
Anqi Xiong
Affiliation:
Karolinska Institutet
Start Date:
2025-03-15
End Date:
2026-04-01
Primary Classification:
10610: Bioinformatics and Computational Biology (Methods development to be 10203)
Webpage:
Allocation
Abstract
The aim of the project is to restore the lost of dopaminergic neurons in Parkinson diseases. We generate dopaminergic neurons from astrocyte by cell reprogramming and we use single cell level sequencing to evaluate the reprogramming induced neurons.