In this project I aim to study a group of ancient hunter-gatherers living in South Africa 2000-10000 years ago. The focus will be on diploid analyses where these individuals genomic characteristics will be compared with modern individuals from the 1000 genome project as well as with a couple of modern day Khoe-San populations living in the nearby area. The hypothesis is that this ancient group of people are the ancestors of modern day Khoe-San populations, but how has different demographic events and possible changes in selection pressure shaped the Khoe-San people through time? Several of the project's analyses (using a larger set of ancient South African individuals) have already been made on NAISS projects on Uppmax, but these analyses have mainly focused of pseudo-haploid data where also low coverage individuals can be included. In order to explore the full genomes of diploid data I would like to use the resources on Dardel. I am using the storage project NAISS 2024/2-10 on klemming for data handling and all necessary data, such as VCF files, are already available. However, I do lack the resources for computing the analyses.