SUPR
ONS RNA methylation landscape
Dnr:

NAISS 2024/23-726

Type:

NAISS Small Storage

Principal Investigator:

Anna Wredenberg

Affiliation:

Karolinska Institutet

Start Date:

2025-01-07

End Date:

2026-01-01

Primary Classification:

10602: Biochemistry and Molecular Biology

Webpage:

Allocation

Abstract

We are interested in whether changes in the mitochondrial methylation potential affect cellular RNA methylation homeostasis. We have performed long-read direct RNA sequencing using Oxford Nanopore sequencing technology on RNA extracted from skeletal muscles of mice deficient in the mitochondrial SAM transporter.