ONS RNA methylation landscape
Dnr:
NAISS 2024/22-1624
Type:
NAISS Small Compute
Principal Investigator:
Anna Wredenberg
Affiliation:
Karolinska Institutet
Start Date:
2024-12-26
End Date:
2025-07-01
Primary Classification:
10602: Biochemistry and Molecular Biology
Webpage:
Allocation
Abstract
We are interested in whether changes in the mitochondrial methylation potential affect cellular RNA methylation homeostasis. We have performed long-read direct RNA sequencing using Oxford Nanopore sequencing technology on RNA extracted from skeletal muscles of mice deficient in the mitochondrial SAM transporter.