In this work, I would like to investigate the effect of heterogenous roughness created by dissolution process in turbulent channel flows for different Prandtl numbers. I have already succeeded in conducting simulation and statistical estimate at Re_tau=180 with Pr=1. We would like to extend the investigation to higher Pr or Sc numbers, up to Sc to 10. Therefore, I would like to perform two analyses in the current allocation: (1) With the same coupling time, how is the behaviour of the Sc in relation to the roughness profile; (2) What is the effect of the surface roughness effect for different Sc or Pr numbers if the we imposed the same heterogenous roughness pattern. The result would be of interested for providing insight to understand how roughened surfaces are created in engineering materials and in nature under forced flow condition.