SUPR
Interactions between antibiotics and multicharged cations
Dnr:

NAISS 2024/22-1592

Type:

NAISS Small Compute

Principal Investigator:

Ran Friedman

Affiliation:

Linnéuniversitetet

Start Date:

2025-01-01

End Date:

2026-01-01

Primary Classification:

10407: Theoretical Chemistry

Webpage:

Allocation

Abstract

This is a project carried out by a guest student who cannot apply on her own. The project deals with better understanding of disabilities mediated by the drugs known as fluoroquinoles, which is likely related to their binding to multicharged cations in the body. Quantum chemical calculations will be carried out to characterise these interactions and examine which ions bind better than others to fluoroquinolone- and tetracycline antibiotics..