Computational biology is a hot field - what with the noble prize in chemistry for 2024 just being awarded in this area of research. Applicant and co-applicants have long worked in this field and contributed pioneering efforts in development of methods as well as state-of-the-art applications. Here, we apply for computer resources to work on force field development, to study enzyme catalysis and to work on drug design for membrane proteins. All these lines of work are well-established in the groups and we have long experience using HPC resources. At least 10-12 people will share the resources.