We are working on new methods to integrate large amounts of data to derive mechanistic insights, with a particular focus on T cells but we have also reached into currently, B cells, covid, toxoplasma and other systems. Our focus is on the computational methods development Currently our primary data analysis focus is on developing a new toolkit for single-cell multiomics analysis. For the coming year, we will increase our focus on telomere length analysis In this extended allocation, we are asking for more space to be able to finish a revision of https://www.biorxiv.org/content/10.1101/2023.03.19.533267v2