Various causes of chronic hepatic injury and inflammation can lead to fibrosis and cirrhosis, potentially predisposing individuals to hepatocellular carcinoma. Despite extensive research, the molecular mechanisms underlying liver fibrosis and its associated progression to cancer remain incompletely understood. In this project, the compute source will be used for analyzing both bulk and single-cell transcriptomics data from different models to study the dysregulated processes underlying chronic liver disease including differential expressed genes, molecular pathways, and transcription factor, deconvolution of cell types.