Molecular Dynamics (MD) simulations can be used to complement experimental data and proved to be powerful tools to aid to solve and validate structures and dynamics of proteins. By combining these two methods with experimental data, they can prove previously unexplained changes and behaviors in proteins. For my project, I would use MD simulations to sample different conformational changes of photoreceptor proteins and try to correlate my findings to previous obtained experimental data (time-resolved crystallography data). The resulting data from the MD simulations can then be directly compared to the time-resolved crystallography data, creating and implementing a new method based on our previous studies.