Transcriptional profiling of neuronal cells and reprogramming process
Dnr:
NAISS 2024/23-232
Type:
NAISS Small Storage
Principal Investigator:
Masahito Yoshihara
Affiliation:
Karolinska Institutet
Start Date:
2024-06-01
End Date:
2025-06-01
Primary Classification:
10610: Bioinformatics and Systems Biology (methods development to be 10203)
Webpage:
Allocation
Abstract
We will investigate the transcriptional and chromatin formation changes of neuronal cells during the differentiation and drug response. In addition, we will attempt to elucidate the mechanism of the reprogramming process using the human early embryonic cell model by transcriptome profiling.