Chromatin landscape in autoreactive B cells
Dnr:
NAISS 2024/22-317
Type:
NAISS Small Compute
Principal Investigator:
Mike Aoun
Affiliation:
Karolinska Institutet
Start Date:
2024-03-20
End Date:
2025-04-01
Primary Classification:
10605: Immunology (medical to be 30110 and agricultural to be 40302)
Webpage:
Allocation
Abstract
It is a follow up project to the published findings regarding the existence of autoreactive B cells in the B cell repertoire and its relevance to autoimmune diseases. Now we want to study the transcriptional profile of these cells from the mouse using RNA and ATAC-seq.