The Swedish bipolar collection (SWEBIC) is a study of genetic and environmental causes of bipolar disorder. SWEBIC includes >11,000 patients with bipolar disorder that were ascertained in two waves (finalized in 2013 and 2022, respectively). Patients were primarily recruited from the bipolar quality assurance registry (BipoläR), and the inclusion criteria were bipolar spectrum disorder and a minimum age of 18. Oral and written consent was required. Whole-blood samples are stored at the Karolinska Institutet Biobank, and an aliquot was used for DNA extraction for further genotyping at the Broad Institute (Boston, US) using Affymetrix 6.0 (Affymetrix, Santa Clara, CA, USA),Illumina OmniExpress chips (Illumina, San Diego, CA, USA), and Illumina GSA-MD arrays (Illumina, San Diego, CA, USA). With this UPPMAX project application, we aim to complete imputation of SNP array data from the SWEBIC study. The Haplotype Reference Consortium (HRC) reference panel v.1.1 will be used as reference. A separate application for access to this panel has been submitted to the European Genome-Phenome Archive / Sanger Institute. Subsequent analyses of imputed data will be conducted locally at the University of Gothenburg and Karolinska Institute. Consequently, data will be deleted from UPPMAX once the imputation protocol is finalized.