Improving CRISPR/Cas9 screening methodologies
Dnr:
NAISS 2024/22-55
Type:
NAISS Small Compute
Principal Investigator:
Bernhard Schmierer
Affiliation:
Karolinska Institutet
Start Date:
2024-02-01
End Date:
2025-02-01
Primary Classification:
30108: Cell and Molecular Biology
Allocation
Abstract
This project will be used to analyse our CRISPR/Cas9 screening data with the aim to set up and optimise alternative CRISPR screening methodologies such as CRISPRi, CRISPRa and CRISPR-X and improve the precision and applicability of these methods.
Linked storage project: sllstore2017103
Keywords: CRISPR; CRISPR/Cas9; genetic screening; lentiviral; pooled screening; CRISPR functional genomics