SUPR
Pancreatic cancer multiomics
Dnr:

NAISS 2023/22-1275

Type:

NAISS Small Compute

Principal Investigator:

Daniel Öhlund

Affiliation:

Umeå universitet

Start Date:

2023-12-04

End Date:

2025-01-01

Primary Classification:

30203: Cancer and Oncology

Allocation

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest forms of cancer with currently no efficient drug treatments. Our lab aims at understanding the interactions between tumour cells and the surrounding microenvironment. A molecular and functional characterization of the interactions with surrounding stroma might identify novel therapeutic targets. In this project, stroma and cancer cells from a mouse model of PDAC will be characterized using RNA-sequencing and chromatin (ATAC-seq) profiling.