Lineage tracing in single-cell dataset
Dnr:
NAISS 2023/22-1208
Type:
NAISS Small Compute
Principal Investigator:
Qirong Lin
Affiliation:
Karolinska Institutet
Start Date:
2023-11-20
End Date:
2024-06-01
Primary Classification:
10203: Bioinformatics (Computational Biology) (applications to be 10610)
Webpage:
Allocation
Abstract
Although many developmental models of tissue formation and organized cell differentiation have been addressed, how clonally related populations of cells remains puzzling. Here we want to use computational tools to discover clonally related cells and dissect the regulatory mechanism behind them through computational analysis.