Mosaic loss of chromosome Y (mLOY) in immune cells: decoding functional consequences and disease risks
Dnr:
NAISS 2023/22-1081
Type:
NAISS Small Compute
Principal Investigator:
Josefin Bjurling
Affiliation:
Uppsala universitet
Start Date:
2023-11-09
End Date:
2025-01-01
Primary Classification:
10609: Genetics (medical to be 30107 and agricultural to be 40402)
Webpage:
Allocation
Abstract
The project will use in-house and external datasets to study the functional outcomes of LOY mosaicism and how LOY in blood cells is associated with risk of disease in other organs. All data is either generated from established cell lines or downloaded from open access databases.