Twisted bilayer graphene (TBG) hosts a set of moiré bands which become flat in the magic angle limit. As part of my PhD I investigated how lattice defects such as non-magnetic impurities and vacancies in TBG induce charge modulations both in the atomic and moiré scale due to the presence of these moiré bands. In this project I will continue to investigate how these defects affect the low-energy electronic structure of the system in the normal state and also extend the investigation to the superconducting state, where a nematic order has been showed to appear.