SUPR
Biophysical data analysis and simulation
Dnr:

NAISS 2023/23-286

Type:

NAISS Small Storage

Principal Investigator:

Emil Marklund

Affiliation:

Uppsala universitet

Start Date:

2023-05-10

End Date:

2024-06-01

Primary Classification:

10603: Biophysics

Webpage:

Allocation

Abstract

I will use these resources to perform different types of data analysis and simulations, mainly of transcription factor - DNA binding and target serch. We have previously shed light on how transcription factors manage to find their DNA targets in bacteria (Marklund et al, Nature, 2020, https://doi.org/10.1038/s41586-020-2413-7) (Marklund et al, Science, 2022, https://doi.org/10.1126/science.abg7427) and I am currently investigating how this process can work in the larger and more complex genomes of mammalian cells.