Oral health is tightly associated with well-being and quality of life. Habitual consumption of sugar, daily habits to keep oral hygiene, microbiome profile are among factors responsible for oral health. Oral microbes convert sugar to acids which corrodes tooth enamel, which in the long run causes dental caries. However, some people seem to be more prone to dental caries than the others, which highlight the individual variations in e.g., oral microbiota or other unknown individual factors. Here we hence aim to disentangle factors responsible for individual variations in oral health and to classify individuals according to their risk of developing dental caries. To achieve these aims, we collected saliva samples of 206 adults and 208 adolescents aged 17-79 years old collected in Umeå, northern Sweden. Dietary data, habits related to oral hygiene, genetic variations underlying taste sensing capacity and preference, as well as microbiota profiles have been collected. Metabolome and sugar profiling analysis have been run on these samples to obtain sugar and metabolome profiles of these participants. This information will serve as a rich source of information to further disentangle the contribution and associations of each variable with oral health indicators. With this information, we will be able to obtain better understanding on individual variations in oral health. Classification of individuals to high or low risk of developing dental caries will allow for better reallocation of medical treatment on high-risk individuals, which allow for early intervention on the progression of dental caries in such individuals.