SUPR
Single-cell analysis of pediatric brain tumor reccurence
Dnr:

sens2022546

Type:

SNIC SENS

Principal Investigator:

Fredrik Swartling

Affiliation:

Uppsala universitet

Start Date:

2022-05-24

End Date:

2024-06-01

Primary Classification:

30203: Cancer and Oncology

Allocation

  • Castor /proj at UPPMAX: 5000 GiB
  • Cygnus /proj at UPPMAX: 5000 GiB
  • Castor /proj/nobackup at UPPMAX: 1000 GiB
  • Cygnus /proj/nobackup at UPPMAX: 1000 GiB
  • Bianca at UPPMAX: 2 x 1000 core-h/month

Abstract

We are analyzing single cell RNA Seq data from pediatric brain tumor patients at primary diagnosis and at recurrence in a clinical study we are conducting at Uppsala University Hospital and in collaboration with Barntumörbanken, Karolinska Hospital. The data is pseudonymised but can be coupled to individuals needs and need to be handled as sensitive data. The study is conducted in order to follow molecular changes from primary diagnosis to recurrence with the intention to find better understanding of the relapse process but also to find new clues for better treatment of these devastating childhood brain tumors.