SUPR
Validation of a Questionnaire-Based Anti-Inflammatory Diet Index (AIDI) as a Predictor of Low-Grade Inflammation in a Cohort of Swedish Men
Dnr:

simp2022005

Type:

SNIC SENS

Principal Investigator:

Joanna Kaluza

Affiliation:

Warsaw University of Life Sciences, Poland

Start Date:

2022-02-10

End Date:

2025-03-01

Primary Classification:

30302: Public Health, Global Health, Social Medicine and Epidemiology

Webpage:

Allocation

  • Castor /proj at UPPMAX: 1000 GiB
  • Cygnus /proj at UPPMAX: 1000 GiB
  • Castor /proj/nobackup at UPPMAX: 128 GiB
  • Cygnus /proj/nobackup at UPPMAX: 128 GiB
  • Bianca at UPPMAX: 2 x 1000 core-h/month

Abstract

There is evidence that diet may be associated with markers of inflammation. Until now, the only dietary inflammatory index to our knowledge developed for a Nordic population is the Anti-Inflammatory Dietary Index (AIDI). The AIDI was developed and validated in a population of 3502 Swedish women (aged 56-74) from the Swedish Mammography Cohort with high sensitivity CRP (hsCRP) <20 mg/L. We hypothesize that the previously developed AIDI could be a valid tool to predict low-grade systemic inflammation in a cohort of middle-aged and elderly men as well. Therefore, the aim of this project is validation and further developing the AIDI as a tool to assess anti-inflammatory potential of diet in the Cohort of Swedish Men - Clinical (COSM-Clinical) subcohort (about 4800 men who participated in a clinical health exam during 2010-2017). To the validation we plan to use hsCRP and other low-grade systemic inflammation-related biomarkers.