Protein biomarkers (proteomics) in relation to risk of cardiometabolic diseases.

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Dnr:

simp2020014

Type:

SNIC SENS

Principal Investigator:

Olga Titova

Affiliation:

Uppsala universitet

Start Date:

2020-10-19

End Date:

2025-11-01

Primary Classification:

30302: Public Health, Global Health, Social Medicine and Epidemiology

Webpage:

https://www.simpler4health.se/

Allocation

Cygnus /proj at UPPMAX: 300 GiB
Cygnus /proj/nobackup at UPPMAX: 128 GiB
Bianca at UPPMAX: 1 x 1000 core-h/month

Abstract

The associations of different protein biomarkers with risk of cardiometabolic disease have not been fully established. The aim of this project is to assess the role of protein biomarkers (proteomics) for risk of various cardiometabolic diseases, with focus on ischemic heart disease (myocardial infarction), ischemic stroke, hemorrhagic stroke, heart failure, atrial fibrillation, abdominal aortic aneurysm, aortic valve stenosis, venous thromboembolism, and type 2 diabetes mellitus.