SUPR
Pain chronification
Dnr:

NAISS 2023/5-91

Type:

NAISS Medium Compute

Principal Investigator:

Saida Hadjab

Affiliation:

Karolinska Institutet

Start Date:

2023-03-31

End Date:

2024-04-01

Primary Classification:

10203: Bioinformatics (Computational Biology) (applications to be 10610)

Secondary Classification:

30108: Cell and Molecular Biology

Tertiary Classification:

30105: Neurosciences

Allocation

Abstract

Aim: The goal of this grant is i) to provide the first comprehensive and integrative map of the transcriptomic changes in the peripheral sensory system, at the single cell level, in different neuropathic pain models ii) to use this knowledge to investigate whether we can prevent or reverse the epigenetic and transcriptomic state modifications and pain sensitisation observed after peripheral nerve injury.