The objective of this project is to better understand the different turbulent drop breakup mechanisms. This could be beneficial to various applications and industries including the food industry where more efficient drop breakup in High-Pressure Homogenizers (HPH) and Rotor-Stator Mixers (RSM) is needed to reduce energy consumption. The overall aim is to improve our fundamental understanding of turbulent drop breakup in HPHs and RSMs. This project includes both an experimental part (breakup visualization in a scale-up model) and resolved Direct Numerical Simulation (DNS). A scale-up model of an HPH gap has been used for the experimental phase of the project and DNS simulations are being performed on the same HPH gap geometry. We will use our DNS results along with the results from the experimental phase of the project to understand how the local and instantaneous flow-field in the region surrounding the drop participate in deforming and breaking it.