We are interested in understanding the role of chromatin-associated RNA (caRNA) in the regulation of chromatin compaction. We have already carried out RNAi experiments to deplete exosome subunits in S2 cells (Drosophila melanogaster) and we carried out RNA-seq experiments to detect caRNAs that are exosome-sensitive. In order to investigate the biological relevance of the impaired abundances of caRNAs, we have performed a ATAC-seq to correlate RNA levels with chromatin compaction genome-wide.