iCBT genomics
Dnr:
sens2019555
Type:
SNIC SENS
Principal Investigator:
James Crowley
Affiliation:
Karolinska Institutet
Start Date:
2019-08-23
End Date:
2025-03-01
Primary Classification:
30107: Medical Genetics
Webpage:
Allocation
- Castor /proj at UPPMAX: 3000 GiB
- Cygnus /proj at UPPMAX: 3000 GiB
- Castor /proj/nobackup at UPPMAX: 500 GiB
- Cygnus /proj/nobackup at UPPMAX: 500 GiB
- Bianca at UPPMAX: 2 x 1000 core-h/month
Abstract
In this project, we aim to identify genetic predictors of response to internet-based cognitive behavior therapy (iCBT). For each individual (total N ~3000), we will have SNP genotype data from a microarray and clinical response information. Analyses will include a genome-wide association study (GWAS) of response to iCBT as well as analyses focused on polygenic risk scores for a variety of phenotypes.